We studied the impact of a genetic variant (SNP in our case) on different gene regulatory traits:
All linear regressions were performed using the R package Matrix eQTL.
We tested SNPs with a minor allele frequency above 5% and falling in a +/- 100 Kb region around each gene (in our data, it represents ~ 3M SNPs).
A SNP can be missing because:
A gene can be missing because :